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P. A. College of Engineering and Technology , Pollachi , India
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P. A. College of Engineering and Technology , Pollachi , India
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Sri Eshwar College of Engineering , Coimbatore , India
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MAEER’S MIT , Mumbai , India
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SRM Institute of Science and Technology (FSH) , Chennai , India
P.A. College of Engineering and Technology , Pollachi , India
The problem of brain tumors is a range of different subtypes, which have a variety of clinical forms, and the diagnosis and treatment of tumors is a challenging task. This paper introduces a hybrid deep learning system that combines genomic profiling with MRI image analysis to provide an effective brain tumor subtyping. The framework is initiated by the preprocessing of MRI images, which is followed by grayscale conversion and noise reduction as done by Fast Non-Local Means (FNLM) filtering. This will aid in ensuring that important structural data is retained with minimal irrelevant noise. To conduct segmentation, the UNet++ framework is used, which is the best-performing architecture in medical image analysis. UNet++ enhances the conventional UNet by adding embedded skip routes, which allows a more productive information exchange between encoder and decoder networks, improving the accuracy of segmentation. The extraction of features is conducted by a local binary pattern (LBP), Gray-Level Co-occurrence Matrix (GLCM), and Discrete Wavelet Transform (DWT). These methods are able to reproduce both the frequency domain and textural characteristics of the tumor areas. The variables are further narrowed down to the most relevant ones by the Minimum Redundancy Maximum Relevance (mRMR) algorithm, thus only the most relevant features are taken in the classifier. The classification is done by an improved variant of the AlexNet that is optimized with the addition of batch normalization, global average pooling, and local response normalization parameters to minimize overfitting and maximize learning effectiveness. The model postulated in this study has a high performance of 99.79 %accuracy, 96.82 %sensitivity, 98.32 %specificity, and 98.61 %precision. These findings indicate the effectiveness of the hybrid approach, combining handcrafted characteristics and deep learning in early and confident brain tumor subtyping, which has considerable potential to enhance the level of diagnostic accuracy and individual treatment approaches in neuro-oncology.
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